MAP kinase phosphatase



MAP kinase phosphatase (MKP) or Dual specificity phosphatase (DUSP) are phosphatases which reverse the activation of MAP kinases by dephosphorylating tyrosine or threonine residues.

3D Structures of MAP kinase phosphatase
3ezz – hMKP-2 (mutant) or DUSP-HVH2 - human

2fys - hMKP-3 peptide or DUSP-5 +rMAP kinase – rat

1hzm - hMKP-3 or DUSP-5

1mkp - hMKP-3 or DUSP-5 (mutant)

3lj8 – hMKP-4

2ouc, 2oud, 1zzw - hMKP-5 or DUSP-10

2wgp – hMKP-6 or DUSP-14

2vsw - hMKP-7 or DUSP-16

1j4x – hDUSP-3 (mutant)+peptide

2g6z – hDUSP-5

2rf6, 2q05 – DUSP – Vaccinia virus